Feasibility of Utilizing the Infinitome Program to Evaluate Abnormal Large Scale Brain Networks in Alzheimer's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4
- 试验地点
- 1
- 主要终点
- Number of Subjects Whose Images Completed Analysis
研究概览
简要总结
The Infinitome Program from Omniscient has the ability to identify abnormal brain networks or connectomes using resting state functional MRI (rs-fMRI). This technology, which visualizes brain networks in three dimensions, was originally developed to ensure neurosurgeons avoid inadvertently lesioning cognitively eloquent brain regions during surgical operations. The potential of Infinitome in identifying connectome dysfunction for neurodegenerative diseases such as Alzheimer's disease has yet to be explored. This diagnostic technique may play a critical role for identifying disease brain networks that may benefit from targeted interventions in clinical trials.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a diagnosis of mild, moderate, or severe Alzheimer's disease
- •Age: 40 - 90 Years
- •Patients who are clinically indicated for an MRI
排除标准
- •fMRI contraindicated (eg. Implantable device, pacemaker, metallic implants, etc.)
- •Subject unable to tolerate sitting for a one hour fMRI
- •Other concerns as determined by the investigator
结局指标
主要结局
Number of Subjects Whose Images Completed Analysis
时间窗: 4 months
Percent of subjects whose images were uploaded and analyzed by the Infinitome program. Range: 0-100. Higher percentage indicates more completion.
Number of Participants Who Completed Rs-fMRI
时间窗: 4 months
Percent of subjects who complete the sequence of the fMRI protocol. Range: 0-100. Higher percentage indicates more completion.
次要结局
未报告次要终点