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Clinical Trials/NCT03452202
NCT03452202
Recruiting
Not Applicable

Using tDCS in Speech-based Stroke Rehabilitation

NYU Langone Health2 sites in 1 country24 target enrollmentJanuary 11, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Apraxia of Speech
Sponsor
NYU Langone Health
Enrollment
24
Locations
2
Primary Endpoint
Change in accuracy in recordings from tasks from baseline to post treatment
Status
Recruiting
Last Updated
9 months ago

Overview

Brief Summary

The purpose of this study is to determine whether the effect of treatment for acquired speech impairment can be enhanced by combining effective behavioral treatment with non-invasive brain stimulation. Transcranial direct current stimulation (tDCS), which delivers low-intensity current to the scalp, and is a safe and well-tolerated approach that poses a non-significant risk to participants. tDCS provides low intensity neural stimulation which has been shown to facilitate motor learning in other domains of stroke rehabilitation such as arm motor learning but the potential to enhance speech motor learning has not been explored. This will be examined with a series of single-case experimental designs.

Registry
clinicaltrials.gov
Start Date
January 11, 2019
End Date
October 30, 2026
Last Updated
9 months ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Right-handed
  • Monolingual (English)
  • Single left-hemisphere CVA
  • A minimum of six months post-stroke
  • Clinical diagnosis of apraxia of speech
  • Normal speech perception
  • Passing score on the hearing screening.

Exclusion Criteria

  • Diagnosis of laryngeal voice disorder
  • Dysarthria
  • History of speech impairment prior to CVA
  • Presence of potential tDCS risk factors: damaged skin at site of stimulation;
  • Presence of electrically or magnetically activated implant (including pacemaker);
  • metal in any part of their body;
  • history of medication-resistant epilepsy in the family;
  • past history of seizures or unexplained spells of loss of consciousness.

Outcomes

Primary Outcomes

Change in accuracy in recordings from tasks from baseline to post treatment

Time Frame: Baseline, 6 Months

Subjects will be given speech production tasks. Recordings of tasks will be scored for accuracy to measure speech motor learning

Study Sites (2)

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