NCT00610142已完成2 期
Comparison of Atrophogenic Effect of Hydrocortison 1% Cream and Pimecrolimus 1% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHz Ultrasound of Uninvolved Skin in Patients With Atopic Dermatitis
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- thickness of epidermis
研究概览
简要总结
to explore the atrophogenic potentials of hydrocortison 1% cream and pimecrolimus 1% cream on unaffected forehead skin
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18-60 years
- •diagnosis of atopic dermatitis (Hanifin & Rajka Criteria)
- •patients with atopic dermatitis not affecting the forehead
排除标准
- •pregnancy / nursing mothers
- •women in reproductive age without adequate contraception
- •severe atopic dermatitis (IGA >= 4)
- •UV-Therapy in past 4 weeks
- •patients receiving any topical treatment on the face in past 6 month
研究组 & 干预措施
1
Active Comparator
干预措施: pimecrolimus 1% cream (Drug)
2
Active Comparator
干预措施: hydrocortison 1% cream (Drug)
结局指标
主要结局
thickness of epidermis
时间窗: 4 weeks
次要结局
- thickness of dermis(4 weeks)
研究者
研究点 (1)
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