Effect of anesthesia type on cognitive functions

Not Applicable

Completed

• Conditions: Postoperative cognitive dysfunction; Anaesthesiology - Anaesthetics; Mental Health - Other mental health disorders

• Registration Number: ACTRN12613000362796
• Lead Sponsor: Dpt. of Anesthesia and Intensive Care of the Faculty of Medicine Plzen - Charles University Prague

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

patients undergoing elective resection of intervertebral disc herniation
given and signed informed consent
Czech as the native language
finished high school

Exclusion Criteria

Abnormal results of preoperative neuropsychological and electrophysiological tests
Disease of central nervous system
Addiction (also in history)
Psychiatric disease, use of psychiatric medication
Sleep apnoea syndrome
Perception disorder
Allergy or intolerance of drugs used for anesthesia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
difference in postoperative psychometric test scoring (Digit Span Backward test, Letter Naming Sequencing test, Digit Span Forward test, Trail Making test, Mental Control test, Stroop test, Verbal fluency)[preoperative, day 1, 7, 40 after anesthesia];difference in electrophysiologic examination results (Event-related potentials – Mismatch negativity and P3 component analysis)[preoperative, day 1, 7, 40 after anesthesia]

Secondary Outcome Measures

Name	Time	Method
presence of postoperative nausea and vomiting[day 1 after anesthesia];postoperative pain measured by visual analogue scale[day 1 after anesthesia]