A randomized, double-blinded, controlled trial of adding a short burst of corticosteroid to the conventional treatment of H1 antihistamines

Phase 4

Recruiting

• Conditions: Acute urticaria, patient, Steroids, H1- Chronic urticaria; Patients visit emergency room at King chulalongkorn memorial hospital (KCMH) Age between 18- 50 years Pateint who meet the following criteria of acute urticarial; Out- Allergic reaction, Corticosteroid&#44

• Registration Number: TCTR20180321001
• Lead Sponsor: Rachada

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-03-21
• Study Completion: 2018-10-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

Patients visit emergency room at King chulalongkorn memorial hospital (KCMH) age between 18-50 years who meet the following criteria of acute urticarial such as
1.eruption of wheals, central swelling of various sizes, with or without surrounding erythema; with or without angioedema
2.pruritus or occasional burning sensation
3.skin returning to normal appearance, usually within 1-24 hours

Exclusion Criteria

1.patients who have urticarial for more than 48 hours
2.have severe underlying disease such as heart disease, kidney disease, liver disease
3.pregnancy
4.history of CPM, steroid, antihistamines allergy
5.history of antihistamine or steroid uses within 48 hours before ED visit
6. diabetes mellitus
7.suspected of more severe disease or severe allergic reaction
8.patients who don’t have puritus
9.patients who have history of chronic urticaria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Itch score 60 minutes visual analog scale

Secondary Outcome Measures

Name	Time	Method
Recurrent rash 1 week Binary outcome