Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment

Not Applicable

Completed

• Conditions: Dentine Hypersensitivity
• Interventions: Procedure: Cocorico; Procedure: Colgate; Procedure: Nano P; Procedure: Sensodyne

• Registration Number: NCT02018783
• Lead Sponsor: Federal University of São Paulo

Brief Summary

The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste. One hundred and thirty-eight hypersensitive teeth were diagnosed and randomized into four groups according to the therapeutic agent of each desensitizing cream tested: 1) strontium acetate and calcium carbonate, 2) calcium carbonate and arginine 8%, 3) calcium phosphate nanoparticles and 4) a control toothpaste. The desensitizing creams were applied according to the manufacturer's instructions. Cervical dentin hypersensitivity was assessed at baseline, immediately, 24 hours and 30 days after the treatment. Cold and evaporative tests were used to assess the sensitivity level.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04
• Primary Completion: 2013-08
• Study Completion: 2013-08
• Status Verified: 2013-12
• Study First Submitted: 2013-12-07
• Study First Submitted QC: 2013-12-17
• Last Update Submitted: 2013-12-17
• Study First Posted: 2013-12-23
• Last Update Posted: 2013-12-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

• subjects 18 years or older
• in good general and oral health; have complaint of CDH in teeth distributed in all 4 quadrants
• not making use of desensitizing agents
• not having undergone periodontal treatment over the past 3 months
• respond to evaporative stimulus with a score ≥ 1.5 cm on VAS

Exclusion Criteria

• patients who presented restorations and caries near the exposed dentin of the hypersensitive teeth
• who made frequent use of painkillers, anti-inflammatory and antidepressants drugs

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Cocorico	Cocorico	Digital application for 60 seconds
Colgate	Colgate	Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure
Nano P	Nano P	Slow-speed handpiece with a Robson brush for 10 seconds
Sensodyne	Sensodyne	Digital application for 60 seconds.

Primary Outcome Measures

Name	Time	Method
cervical dentin hypersensitivity	30 days	The cervical dentin hypersensitivity was evaluated by an air blast (evaporative stimulus) for 5 seconds, and by a tetrafluoroethane spray (cold stimulus) for 5 seconds.

Trial Locations

Locations (1)

Periodontics Clinic, Department of Dentistry; 🇧🇷 Diamantina, Minas Gerais, Brazil