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临床试验/NCT00298207
NCT00298207已完成不适用

Walking Intervention in African American Adults With Newly Diagnosed Hypertension

University of Illinois at Chicago2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2001年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
20
试验地点
2
主要终点
Change in Systolic and diastolic blood pressure over duration of study

研究概览

简要总结

High blood pressure (hypertension) is one the most common and serious chronic diseases among Americans, especially among the African Americans. The purpose of this study is to explore the effect six month long walking intervention on blood pressure in adult African American with a newly diagnosed high blood pressure (hypertension). The hypothesis is that the group with encouragement to walk extra 30 minutes a day for 5-7 days a week may lower their blood pressure compared to the control group without the encouragement.

详细描述

Hypertension is a very common and serious chronic disease, which affects approximately 50 million people in the United States. Defined by systolic blood pressure (SBP) of 140 mm Hg or higher or diastolic blood pressure (DBP) of 90 mm Hg or higher, hypertension increases the risk for adverse cardiovascular and renal outcomes, such as myocardial infarction, stroke, congestive heart failure, end-stage renal disease, and peripheral vascular disease. Data from as early as the 1960's indicates that the disease disproportionately effects subgroups of the population, with non-Hispanic African Americans having an age-adjusted prevalence of hypertension (32.4%) almost 40% higher than that noted in non-Hispanic whites (23.3%) and Mexican Americans (22.6%). Although hypertension-related mortality seems to be declining among African Americans, it continues to be a problem which disproportionately affects African Americans more than Whites, particularly in younger age groups.

The management of hypertension is of particular importance for primary care providers, due not only to its prevalence but also because it is a modifiable risk factor for cardiovascular diseases. Although, there are a number of medications available for lowering blood pressure, the first step in managing hypertension should be life-style modification, including weight reduction, increased physical activity, and restriction of dietary sodium and alcohol intake.

Walking seems to be one of the safest and simplest exercises for hypertensive patients of all age groups. Combinations of walking, jogging and bicycling have been shown to be effective in managing hypertension, but there are inherent risks associated with strenuous exercises like jogging and bicycling. Additionally, as most hypertensive patients tend to be overweight, jogging may not be an easy exercise for them. The positive effect of brisk walking on hypertension has been demonstrated in postmenopausal women. Despite the recognized importance of finding ways to effectively manage hypertension in African Americans, there is a paucity of studies on the impact of walking in this population. The purpose of this research was to study the impact of walking an extra 30 minutes a day on blood pressure in 25 to 59 year old African Americans with newly diagnosed hypertension.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Other
盲法
Single (Investigator)

盲法说明

Single Blind

入排标准

年龄范围
25 Years 至 59 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • African American male
  • newly diagnosed hypertension
  • between age 25 to 59

排除标准

  • Not being able to walk unassisted,
  • not having telephone access,
  • being involved in regular sports activity,
  • taking any type of antihypertensive medications,
  • advanced renal, cardiovascular, or obstructive pulmonary disease.

结局指标

主要结局

Change in Systolic and diastolic blood pressure over duration of study

时间窗: Blood Pressure will be measured at study entry, at three months and at six months

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Augustine J. Sohn

Associate Professor at Department of Family Medicine

University of Illinois at Chicago

研究点 (2)

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