Infectious Agents Exposure : Archiving in Dental Plaque

• Conditions: Infection; Dental Calculus

• Registration Number: NCT03864952
• Lead Sponsor: University Hospital, Brest

Brief Summary

We are studying the possibility of using dental calculus as a reservoir for the genes of an infectious agent that has infected the patient in previous months; as it is done to highlight climate change in ice samples.

Detailed Description

From a sample of people who have had a microbiologically well-documented infection, we will study the possibility after genomic amplification to find, three to 12 months after genetic sequences of the infectious agent in the dental calculus of the person. The people will be recruited according to a large panel of infectious agent (gram + and gram bacterium, mycobacteria, parasite, fungus, DNA, RNA or retrovirus) and, of course, the presence of dental calculus.

Study Timeline

• Status Verified: 2019-03
• Study Start: 2019-03-04
• Study First Submitted: 2019-03-05
• Study First Submitted QC: 2019-03-05
• Last Update Submitted: 2019-03-05
• Study First Posted: 2019-03-06
• Last Update Posted: 2019-03-06
• Primary Completion: 2019-09-04
• Study Completion: 2019-09-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• three months before, having been infected with a documented pathogen
• this infection must have been clinically obvious
• the patient must have dental calculus

Exclusion Criteria

• to be under 18 years old
• to be incapable to consenting
• a tartar removal since the infection

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
successful detection of pathogen	3 to 12 months	detection of infectious agent

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France