Relationships between genome DNAs in dental plaque and periodontal disease
Not Applicable
- Conditions
- periodontal disease
- Registration Number
- JPRN-UMIN000041522
- Lead Sponsor
- Department of Dental Anesthesiology, Okayama University Hospital, Okayama University
- Brief Summary
1) The proportions of the constituent bacterial flora in periodontal pockets were examined in 10 persons with Down syndrome and 6 persons without Down syndrome. The results showed that the mean component ratio of Actinomycetales was significantly higher in preventive dental patients than in patients with Down's syndrome. 2) Plaques were collected from six patients with Down syndrome after about six months of treatment. The results showed a predominant increase in Spirochaetales.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
Not provided
Exclusion Criteria
1) Woman with pregnant or with possibility of pregnant. 2) Patients with difficulty in continuous consultation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Components of the plaque, pocket depth, bleeding on probing, mobility
- Secondary Outcome Measures
Name Time Method As the first examination, primary outcomes are evaluated and the plaque is kept. Six month after treatment, same examination and the keeping sample plaque are made.