Periodontal parameters and microbiome composition of the tooth pocket under anti-cytokine therapy in patients with chronic inflammatory diseases under targeted anti-cytokine therapy
- Conditions
- periodontitis, chronic inflammatory disease
- Registration Number
- DRKS00032473
- Lead Sponsor
- Innere Medizin I, UKSH Kiel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Diagnosed chronic inflammatory disease
- First-time targeted anti-cytokine therapy upcoming
- Participation in the Biological Follow Up Study
- Written informed consent
Exclusion Criteria
- Edentulousness
- Ongoing periodontal therapy
- Need for endocarditis prophylaxis
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of periodontal parameters (BOP, sulcus depths)<br>
- Secondary Outcome Measures
Name Time Method Change in the oral microbiome (diversities, bacterial composition)