Oral Microbiota and Oral Status of Adult Patients With Autism Spectrum Disorders (MICAA: MICrobiota Autism Adults)
- Conditions
- Autism Spectrum Disorder
- Registration Number
- NCT05910424
- Lead Sponsor
- Central Hospital, Nancy, France
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 37
Inclusion Criteria:<br><br> - A person (or legal representative) who has received full information about the<br> organisation of the research and accept to participate and the use of his or her<br> data.<br><br> - Adult with autism spectrum disorder, men or women aged between 18 and 60.<br><br> - Member of a social security scheme or beneficiary of a medical insurance<br><br>Exclusion Criteria:<br><br> - Children under 18 with autism spectrum disorder<br><br> - Use of medication or situations that may affect the microbiota (use of antibiotics,<br> probiotics, steroidal or non-steroidal anti-inflammatory drugs in the last 3 months,<br> strict mouth breathing)<br><br> - Smoking<br><br> - Very lingual position of the teeth hindering clinical assessment of the periodontium<br><br> - Patients who have had periodontal treatment for less than 6 months<br><br> - Persons covered by articles L. 1121-5 to L. 1121-7 and L1122-2 of the French Public<br> Health Code:<br><br> - Pregnant women, women in labour or breast-feeding mothers<br><br> - Persons deprived of their liberty by a judicial or administrative decision<br><br> - Persons unable to give their consent<br><br> - Person under psychiatric care by virtue of articles L. 3212-1 and L. 3213-1 of the<br> Public Health Code<br><br> - Minor (not emancipated)
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Presence of periodontopathogenic bacteria (harmful for gums)
- Secondary Outcome Measures
Name Time Method Assessment of the presence of parasites Entamoeba gingivalis subtype 1 (ST1) and subtype 2 (ST2) and Trichomonas tenax;Assessment of the periodontal status of patients with Autism Spectrum Disorder;Assessment of the dental condition;Assessment of oral hygiene;Collection of data about lifestyle habits (oral and dental hygiene, diet, activity, etc.) and drug treatments that may influence the clinical parameters observed