Identification of Microorganism and Biomarkers Present in Oral Cavity in Oral Cancer Patients .
Not Applicable
- Conditions
- Health Condition 1: - Health Condition 2: Z00-Z99- Factors influencing health status and contact with health services
- Registration Number
- CTRI/2024/03/064727
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adults (18 to 70 ) who have been diagnosed with oral dysplasia
Adults (18 to 70 ) or who have been diagnosed with oral malignancies.
Healthy controls (18 to 70 ) free of any oral lesions
Exclusion Criteria
•Adults refusing to participate in the study.
•Exclusion criteria for Healthy Participants: Individuals with active dental infection/recent antibiotic use/anti-septic mouthwash use will be excluded from the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method •Identifying relative distribution of microbes and oncogenic cytokines in pre-cancer and cancer as compared to healthy environments <br/ ><br>•To explore potential utility of microbiome & oncogenic cytokines for early detection of oral cancers. <br/ ><br>Timepoint: •Identifying relative distribution of microbes and oncogenic cytokines in pre-cancer and cancer as compared to healthy environments <br/ ><br>•To explore potential utility of microbiome & oncogenic cytokines for early detection of oral cancers. <br/ ><br>
- Secondary Outcome Measures
Name Time Method Identifying relative distribution of microbes and oncogenic cytokines in pre-cancer and cancer as compared to healthy environments <br/ ><br>•To explore potential utility of microbiome & oncogenic cytokines for early detection of oral cancers. <br/ ><br>Timepoint: Identifying relative distribution of microbes and oncogenic cytokines in pre-cancer and cancer as compared to healthy environments <br/ ><br>•To explore potential utility of microbiome & oncogenic cytokines for early detection of oral cancers. <br/ ><br>