MedPath

Effects of a Physical Rehabilitation Program Using the Nintendo Wii on Children With Osteogenesis Imperfecta (OI)

Not Applicable
Terminated
Conditions
Osteogenesis Imperfecta
Interventions
Other: Training with Nintendo Wii console
Registration Number
NCT02542540
Lead Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Brief Summary

Children with osteogenesis imperfecta are described as extremely sedentary and therefore fatigable, which strongly impacts their daily activities. The physical rehabilitation of these children is a fundamental aspect of treatment.

It has been shown that playing Wii console causes the same increase in energy expenditure than practicing moderate exercise, while ensuring user safety. This type of physical exercise with this type of fun game console might have a role in the treatment of OI children on the physical side but also on the psychological side.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
20
Inclusion Criteria
    • Children affiliated to a social security scheme
  • Children diagnosed OI by a competent physician of one of the French specialist centers;
  • OI children type 1 or type 4;
  • Stable OI (far from a fractional episode of at least two months);
  • Children without regular activity on the Nintendo Wii console or other interactive console;
  • Boy or Girl> 6 to 18 years
  • Parents or person having parental authority affiliated to a social security scheme
  • Parents or person having parental authority who signed the consent form for the study.
Exclusion Criteria
    • Children who can not walk;
  • Children with severe OI other than type 1 or type 4;
  • Fracture during the last two months;
  • Surgical intervention within the last 8 months;
  • Inability to understand and follow the protocol;
  • Participation in another clinical study;
  • Children, parents or holder of parental authority refusing the written consent.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
OI Children training with Nintendo Wii consoleTraining with Nintendo Wii consoleTraining for 3 months using the Nintendo Wii console on physical capacity in a group of children with Osteogenesis Imperfecta
Primary Outcome Measures
NameTimeMethod
Change in physical capacityfrom baseline to 3 months

Compare the change in physical capacity between training group of children with OI and control group of children with OI. The physical capacity is measured by maximal oxygen consumption VO2 max (ml/min/kg) measured during incremental exercise on cycle ergometer

Secondary Outcome Measures
NameTimeMethod
Compare endurance of lower limbs between training group and control groupMonth 9

The endurance of the lower limbs will be measured by EMG analysis on incremental torque repetitive exercise

Change in physical capacityFrom baseline to 9 months

Compare the change in physical capacity between training group of children with OI and control group of children with OI. The physical capacity is measured by maximal oxygen consumption VO2 max (ml/min/kg) measured during incremental exercise on cycle ergometer

Compare quality of life between training group and control groupMonth 9

The quality of life will be determined the Index Questionnaire Reintegration to Normal Life (IRVN)

Compare muscle strength between training group and control groupMonth 9

The muscle strength is a composite outcome. It will be assessed by:

* The grip strength (force applied by the hand)

* The maximal quadriceps muscle strength will be measured using an isokinetic dynamometer "Contrex"

Training toleranceBaseline from 9 months

Reentrainment tolerance is a composite outcome. It will be assessed by :

* collecting any events related to WII training or any events related to everyday life (fractures, pain,etc.)

* dropout rate study report

Compare physical inactivity between training group and control groupMonth 9

Physical inactivity will be assessed by the Physical Activity Questionnaire (Q-APS)

Compare functional benefit between training group and control groupMonth 9

The functional benefit will be evaluated by the Functional Independence Measure (FIM)

Compare body fat between training group and control groupMonth 9

Body fat composition will be determined by skinfold measurements

Compare Energy expenditure of lower limbs between training group and control groupMonth 9

Energy expenditure is a composite outcome. It will be measured by collecting the respiratory exchange and heart rate during endurance, tennis and boxing games using the Nintendo WII

Trial Locations

Locations (1)

CHU Saint-Etienne

🇫🇷

Saint-Etienne, France

© Copyright 2025. All Rights Reserved by MedPath