Effects of muscular strength, balance, flexibility, agility and coordination exercises and calcium vitamin ingestion on the function of the muscle / bone of older wonen with osteoporosis

Phase 3

Recruiting

• Conditions: Osteoporosis; Musculoskeletal System; Accidental Falls; Aged; G11.427.410.698.277 I03.350; D04.210.500.247.222.159

• Registration Number: RBR-7d6qr5f
• Lead Sponsor: Complexo Hospital de Clínicas da Universidade Federal do Paraná

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-09
• Last Update Posted: 29 May 2023
• Study Completion: 2024-03-20

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Elderly women; 65 years of age or above on the day of the initial assessments; resident in Curitiba-PR-Brazil; with a diagnosis of osteoporosis by dual energy x-ray (DEXA); able to walk independently a 8 meter flat course, with or without any assistive equipment; presenting a cognitive score in accordance with the Mini Mental state (score 24) regarding the presence or absence of prior formal schooling; not having neurological diseases and/or orthopedic traumas that may prevent the evaluation and exercises execution; not having severe deficiencies (cardiac, respiratory, hepatic, renal, and decompensated hypertension Blood pressure (140 and 90 mmHg); not having any neurologic or trauma-orthopedic diseases with fixations or prostheses with metallic or non-metallic implants, which may prevent the performance of the proposed evaluations or exercises; not having had prior history of upper extremities and Lower Extremity and or spine fracture in the last 4 months or that may impair their performance in the proposed evaluations and exercises; Visual assessment by the Snellen card presenting (score 20 and 70 unilateral), in case of visual impairment, an adequate corrective instrument should be used (glasses or lenses); not having been involved in any regular resistance exercise program in the last 6 months.

Exclusion Criteria

Previous history of fractures of the upper and lower limbs and or spine in the last 4 months; presenting metabolic instability or decompensated cardiovascular disease; having inflammatory and or autoimmune diseases, acute or terminal disease; cancer. Present neurological diseases; osteomalacia; presenting unstable or exercise-induced angina pectoris or myocardial ischemia; presenting type 1 diabetes mellitus; presenting previous diagnosis of: hypercalciuria, hyperparathyroidism, desabsorptive syndromes; using anabolic steroids (for example: synthetic testosterone, Growth hormone (GH); growth factor I (IGF-I) taking part in a regular physical training program; using antiretrovirals and/or anticonvulsants and/or immunosuppressant drugs and/or corticosteroids; making use of current daily or last year alcohol intake above 25g/day; having severe deficiencies (cardiac, respiratory, hepatic, renal, and decompensated hypertension above 140 and 90 mmHg); previous diagnosis of diseases such as: heart valve moderate stenosis, chronic obstructive lung disease (COLD) with Forced expiratory volume (FEV-1) lower 50% previously diagnosed, hypothyroidism with altered levels of thyroid stimulating hormone (TSH) or free thyroxine (T4)T4; hypo or hyper cortisolism; chronic kidney disease with glomerular filtration rate estimated below 30ml/min.1.73m2 according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI).equation; infectious-contagious disease; human immunodeficiency vírus (HIV), hepatitis, and diabetes mellitus with lesions in the target organ of any gravity and difficult to control clinically; using two or more hypoglycemic drugs; insulin therapy or with glycated hemoglobin (HbG) higher 8.5%; patients who experienced clinical complications requiring hospitalization or an emergency unit within the 90 days preceding the evaluations of the study protocol or who were bedridden for the same period, and patients with the following conditions: using medications that could alter body composition or physical performance, any clinically decompensated chronic disease, neurological disease, except for osteoporosis, pregnancy.

Study & Design

• Study Type: Intervention
• Study Design: Not specified