Anaesthesia study comparing two drugs,having different mechanism of actions.The study is done on patients undergoing Gynecological surgery and the technique is Combined Spinal Epidural technique.

Not yet recruiting

Conditions: Noninflammatory disorder of uterus, unspecified,

Registration Number: CTRI/2020/05/025192

Lead Sponsor: Government Medical College and Hospital Jammu

Brief Summary: The study will be conducted in the Post Graduate Department of Anaesthesiology and Intensive Care, Government Medical College Jammu after getting clearance from institutional ethics comittee. The patients enrolled will be explained about the study and a written informed consent will be taken.

INCLUSION CRITERIA:

1. ASA Grade I and II

2. 30-60 years females

3. Scheduled for abdominal hysterectomy

EXCLUSION CRITERIA:

1. ASA Grade > II

2. Patients with contraindications for neuraxial anesthesia

3. Patients with history of local anesthetic allergy

4. Obese patients (BMI > 35)

5. Patients not willing for regional anaesthesia

Using CSE technique drugs will be given to the patients divided in two groups of 30 each and the two drugs dexmedetomidine and fentanyl will be compared. Sensory blockade, Motor blockade, duration of analgesia and sedation will be noted inta operatively and post operatively and will be scored and recorded. All the cardiorespiratory parameters of heart rate, blood pressure and spo2 will be monitored continuously and recorded. Data so collected will be analysed, compared and subjected to statistical analysis.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 60

Inclusion Criteria

1.60 Female patients 2.ASA Grade I and II 3.Scheduled for abdominal hysterectomy.

Exclusion Criteria

1.ASA Grade>II 2.Patients with contraindication for neuraxial anesthesia 3.Patients with history of local anesthetic allergy 4.Obese patients (BMI>35) 5.Patients not willing for regional anaesthesia.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To study and compare effect of dexmedetomidine and fentanyl given epidurally in abdominal hysterectomies with intrathecal bupivacaine using CSE technique.	180 minutes

Secondary Outcome Measures

Name	Time	Method
To see and compare the duration and quality of post operative analgesia & complications if any in two groups.	180 minutes

Trial Locations

Locations (1): Government Medical College and Hospital Jammu
🇮🇳
JAMMU, & KASHMIR, India
Government Medical College and Hospital Jammu
🇮🇳JAMMU, & KASHMIR, India
Dr Shilaga Dhar
Principal investigator
7889433509
sdhar8846@gmail.com