Evaluation by high resolution micro computerized tomography of bone microarchitecture changes in patients with rheumatoid arthritis under anti-TNF therapy.

• Conditions: rheumatoid arthritis requiring anti-TNF alpha treatment; MedDRA version: 9.1Level: HLTClassification code 10039075Term: Rheumatoid arthritis and associated conditions

• Registration Number: EUCTR2008-006256-22-FR
• Lead Sponsor: CHU Saint-Etienne

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-10-31
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

- Men from 18 to 65 years old
- Women from 18 years old to menopause
- Patient with a polyarthritis rhumatoïd ( diagnostic criteria of the ACR) badly controlled by the usual treatments(DAS28>3)
- Patient affiliated or beneficiary of a national insurance system
- Patient with signed consent

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

- Concomitant osseous disease (Paget's disease, osteomalacia...)
- Endocrinopathy defined on biological criteria (Cushing's disease, hyperthyroidism, hypogonadism...)
- Patients under protection of justice
- Refusal consent

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified