Fasting and its effect on Cognitive Functio

Active, not recruiting

• Conditions: Weight Loss; overweight / obesity; Cognitive function; Diet and Nutrition - Obesity; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12616001531404
• Lead Sponsor: CSIRO

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-11-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

Self-reported cognitively healthy participants
Able to undertake a computerised battery
Not currently using a fasting regime for weight management or weight loss

Exclusion Criteria

Smoker
BMI >30
History of mood disorder (e.g., Depression or Anxiety)
Neurological Disease (e.g., Dementia)
Uncontrolled Hypertension
Diabetes (both types)
Lactose intolerant
Coeliac Disease
Nut/Seed allergy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive Function: captured as mean performance on the CSIRO Computerised Fatigue Battery (CFB). The CFB consists of three tasks (Psychomotor Vigilance Task, Interference Task & Arithmetic Task) in each set, with three sets performed per assessment[Baseline (0; 8:30am), +1.5, +3.5, +5.5, +7.5 hours];Cognitive Fatigue: captured as intra-individual variability estimates (e.g., Standard Deviation of Reaction Times, Coefficient of Variation of Reaction Times) during performance on the CSIRO Computerised Fatigue Battery (CFB). The CFB consists of three tasks (Psychomotor Vigilance Task, Interference Task & Arithmetic Task) in each set, with three sets performed per assessment[Baseline (0; 8:30am), +1.5, +3.5, +5.5, +7.5 hours];Subjective Fatigue: Measured with a modified Activation-Deactivation Adjective Check List VAS instrument[Baseline (0; 8:30am), +1.5, +3.5, +5.5, +7.5 hours]

Secondary Outcome Measures

Name	Time	Method
Blood Glucose: Determined via use of a lancing device and blood glucose meter [Baseline (0; 8:30am), +1.5, +2.5, +3.5, +4.5, +5.5, +6.5, +7.5 hours];Satiety & Food Cravings Questionnaire[Baseline (0; 8:30am), +1.5, +2.5, +3.5, +4.5, +5.5, +6.5, +7.5 hours]