Comparison of analgesic effects of Morphine and Indomethacin suppositories in patients with clinical diagnosis of renal colic
- Conditions
- Renal Colic.Unspecified renal colic
- Registration Number
- IRCT2014050514297N2
- Lead Sponsor
- Vice chancellor for research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 158
Patients between 18-85 years old with clinical diagnosis of renal colic referred to emergency ward; Consent to participate in the trial
Exclusion criteria: Patient's refusal for entering the study; Pregnancy; Substance abuse; Taking analgesics 4 hours before referral; Past history of drug reaction to morphine or NSAIDs; Refuse to take rectal analgesic drug; Diarreha; Past history of chronic liver or kidney disease, COPD, Hypercapnea, Mild or severasthma, Sleep apnea syndorme, History of ileus, paralytic, Hypotension, IBD, Chronic Pancreatitis, Chronic bile duct dysfunction, Confusion, Severe anemia,Hipnotic drugs and phenothiazine, Adrenocortical dysfunction, Untreated hypothyroidism, Hypovolemia; Breast feeding; Chronic consumption of NSAIDs; Peritonitis
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The analgesic effect of drugs. Timepoint: Immediately before, 20, 40, 60 and 90 minutes after drugs administration. Method of measurement: Pain scores (VAS).
- Secondary Outcome Measures
Name Time Method Vital sign changes. Timepoint: Immediately before, 20, 40 and 60 minutes after administration of drugs. Method of measurement: Clinical examination.;Nausea and vomiting. Timepoint: Immediately before, 20, 40 and 60 minutes after administration of drugs. Method of measurement: Questionnaire.;Drowsiness. Timepoint: Immediately before, 20, 40 and 60 minutes after administration of drugs. Method of measurement: Questionnaire.;Dry mouth. Timepoint: Immediately before, 20, 40 and 60 minutes after administration of drugs. Method of measurement: Questionnaire.;Allergy. Timepoint: Immediately before, 20, 40 and 60 minutes after administration of drugs. Method of measurement: Clinical examination and Questionnaire.