Effect of Preoperative Hypertension and Controlled Hypotension on Postoperative Delirium in the Elderly
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Degree of delirium
研究概览
简要总结
Comparision of Exposed Factors of Preoperative Hypertension and Intraoperative Controlled Hypotension on Postoperative Delirium in the Elderly under Radical Resection of Head, Neck and Maxillofacial Tumor
详细描述
Postoperative delirium has a higher incidence in elderly patients after general anesthesia,and It is closely related to the type of surgery, the length of surgery, and the patient's physique.Because head and neck maxillofacial radical surgery requires free flap transplantation and longer duration,and hemorrhage is more when the primary focus is removed,Intraoperative blood pressure reduction is needed to reduce bleeding,therefore, hypoperfusion of craniocerebral blood flow will occur.Low cerebral perfusion is closely related to the occurrence of postoperative delirium.Patients undergoing this type of surgery have more preoperative complications,hypertension is particularly common.Therefore, this study mainly studied the correlation between the preoperative blood pressure level and the controlled hypotension level in patients with radical head and neck and maxillofacial tumors and the incidence of postoperative delirium.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent radical anesthesia for oral and maxillofacial malignant tumors in our hospital
- •ASA grade is Ⅰ-Ⅱ
- •Patient is older than 60 years
排除标准
- •The patient has mental and mental disorders (eg schizophrenia, Alzheimer's disease)
- •There was severe anemia before operation (Hb<80g/L)
- •Patients had cerebral vascular complications such as cerebral infarction and lacunar infarction before operation
- •Patients who do not cooperate with this trial
- •Long-term use of sedative drugs or analgesics
结局指标
主要结局
Degree of delirium
时间窗: up to three days after surgery
From the first to the third day after surgery, the patient will be evaluated for delirium using the CAM scale.
次要结局
未报告次要终点
研究者
Zhang Lei
Deputy Chief Physician and Associate Researcher
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
