To compare the efficacy and impact on sexual function of combination of Tadalafil and Tamsulosin versus Tamsulosin alone in the management of Benign prostatic hyperplasia in patients attending Lagos State University Teaching Hospital
Phase 3
- Conditions
- Urological and Genital Diseases
- Registration Number
- PACTR202311592558473
- Lead Sponsor
- Atobatele Kazeem
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- 182
Inclusion Criteria
Patients must be 45 years and above with mild to moderate IPSS (0-19)
Patients with PSA less than or equals 4ng/ml, normal DRE and imaging studies
Patients with peak flow rate less than 15mls/sec and PVR greater than or equals 50mls
Patients who give verbal and written consent to the study
Exclusion Criteria
Patients with severe IPSS, PSA greater than 4ng/ml and peak flow rate greater than 15mls/sec.
Patients with PVR less than 50mls.
Contraindications to study medications.
Patients with no sexual partner during the study period
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method International prostatic symptoms score
- Secondary Outcome Measures
Name Time Method Quality of life, erectile function, maximum urinary flow rate and post-void residual urine volume