NCT06343636已完成1 期
A Phase 1, First-in-human, Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VG-3927 in Healthy Adults
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 115
- 试验地点
- 3
- 主要终点
- Adverse Events
研究概览
简要总结
A Phase 1, First-in-human, Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VG-3927 in Healthy Adults
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Sequential
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The participant is deemed healthy by the principal investigator, as determined by prestudy medical evaluation
- •The participant voluntarily agrees to participate in this study and signs an institutional review board approved informed consent
排除标准
- •The participant has any concurrent disease or condition that, in the opinion of the principal investigator, would make the participant unsuitable for participation in the clinical study
研究组 & 干预措施
Single and Multiple Ascending Dose
Experimental
Ascending single doses and multiple doses for healthy volunteers.
干预措施: VG-3927 (Drug)
Placebo
Placebo Comparator
Matching placebo
干预措施: Placebo (Drug)
Alzheimer's Disease
Experimental
Single Dose Open-label
干预措施: VG-3927 (Drug)
结局指标
主要结局
Adverse Events
时间窗: 28 days post last dose
To evaluate the safety and tolerability of VG-3927
次要结局
未报告次要终点
研究者
研究点 (3)
Loading locations...
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