Effects of White Wine vs. Tea Intake During and an Alcoholic Digestive Following a High Fat, High Calorie Cheese Fondue Meal on Gastric Emptying and Abdominal Symptoms in Healthy Volunteers
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- University of Zurich
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Effect of white wine vs. tea on gastric emptying
Study Overview
Brief Summary
Tradition holds that the intake of different drinks with a meal has an important influence on the digestion of food and postprandial symptoms such as fullness, bloating and satiety; however this assumption have never been subjected to controlled study
A classic example is the Swiss cheese fondue. The intake of white wine, tea and cherry schnapps (Kirsch) are often attributed either positive or negative effects on the gastrointestinal tract.
In this study the effect of white wine vs. tea intake during and an alcoholic digestive following a high fat, high calorie Swiss fondue meal on gastric emptying and visceral perception will be investigated using a randomized, controlled study design.
The fondue will be labeled with non-radioactive 13C octanoate for assessment of gastric emptying by breath-test.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Health Services Research
- Masking
- None
Eligibility Criteria
- Ages
- 19 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •able to communicate well with the investigators and provide written consent
- •Body Mass Index: 19-30 kg/m2
Exclusion Criteria
- •physical co-morbidity requiring active treatment
- •psychiatric (DSM IV) disorders limiting the ability to comply with study
- •use of medications influencing upper GI motility
- •evidence of current drug or alcohol abuse
- •history of gastrointestinal disease or surgery except appendicectomy or hernia repair
Outcomes
Primary Outcomes
Effect of white wine vs. tea on gastric emptying
Time Frame: 4 hours
Secondary Outcomes
No secondary outcomes reported