Effects of a Threshold Trainer on Inspiratory Muscle Strength in Mechanically Ventilated Patients: A Randomized Controlled Trial

Phase 1

• Conditions: Respiratory

• Registration Number: PACTR201909644273809
• Lead Sponsor: Kelebogile Montsho

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-09-26
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

I.Participants should be intubated for at least 48 hours on PSIMV, CPAP, BiPAP or T-piece.
II.Participants should be on FiO2 of 50% and less, PEEP of 8cmH2O or less, SpO2 of 90% and above.
III.Participants should be haemodynamically stable (with BP no less than 100/60 mmHg or more 150/90 mmHg, HR of no more 120 b/minute, temperature no more than 37.50C).
IV.Conscious and able to respond to verbal commands with a GCS of 7/10 and above.
V.Participants should be able to maintain a semi-fowler position for at least 15 minutes.

Exclusion Criteria

I.Participants will be excluded if they are haemodynamically unstable.
II.Participants will be excluded if they have conditions that compromise inspiratory muscle training (e.g flail chest, neuropathies, myopathies, distended abdomen, open abdomen).
III.Participants on sedatives or paralyzing medication at the time of assessment (propofol , dormicum, high levels of morphine etc)
IV.Participants who cannot offer co-operation.
V.Pain with a VAS of more than 8.

Study & Design

• Study Type: Interventional
• Study Design: Not specified