Effect of Carvedilol on Heart functio
Not Applicable
- Conditions
- Breast cancer.Malignant neoplasm of breastC50-C50
- Registration Number
- IRCT2015062922968N1
- Lead Sponsor
- Vice Chancellor for research of Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 50
Inclusion Criteria
inclusion criteria:
all of patient with breast cancer candidate for Herceptin therapy without attention to previous chemotherapy that have Ejection Fraction >50% and normal diastolic function or mild dysfunction
exclusion criteria:patient who have contraindication for Carvedilol;grade 2or 3 AV block; Heart rate <50;systolic blood pressure<90;Asthma;chronic obstructive pulmonary disease ;liver cirrhosis;psoriasis; peripheral vascular disease
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eft ventriculare dysfunction. Timepoint: Before chemotherapy and 3-6-12 month after thet. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method