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Effect of Carvedilol on Heart functio

Not Applicable
Conditions
Breast cancer.
Malignant neoplasm of breast
C50-C50
Registration Number
IRCT2015062922968N1
Lead Sponsor
Vice Chancellor for research of Hamedan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
50
Inclusion Criteria

inclusion criteria:
all of patient with breast cancer candidate for Herceptin therapy without attention to previous chemotherapy that have Ejection Fraction >50% and normal diastolic function or mild dysfunction
exclusion criteria:patient who have contraindication for Carvedilol;grade 2or 3 AV block; Heart rate <50;systolic blood pressure<90;Asthma;chronic obstructive pulmonary disease ;liver cirrhosis;psoriasis; peripheral vascular disease

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
eft ventriculare dysfunction. Timepoint: Before chemotherapy and 3-6-12 month after thet. Method of measurement: Echocardiography.
Secondary Outcome Measures
NameTimeMethod
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