Insulin Pre-treatment for Steroid-associated Hyperglycemia in Pregnant Diabetic Patients
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Number of hospital days until euglycemia in pregnant diabetic patients receiving steroids who are pre-treated with insulin.
研究概览
简要总结
Our objective is to assess whether pre-treatment with a fixed dose of insulin, based on weight, given to pregnant patients with gestational or preexisting diabetes receiving betamethasone can provide adequate glycemic control.
Our hypothesis is that pre-treatment with a weight-based calculated insulin dose will help maintain euglycemia for pregnant patients with gestational and preexisting diabetes after steroid administration, and possibly impact length of hospital admission.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant women with gestational or pre-existing diabetes admitted to the University of Minnesota
- •Must be 18 years or older
- •Must speak English, Spanish, or Somali
- •Patients must receive steroids for fetal lung maturity as part of their hospital course
排除标准
- •Pregnant women with Type 1 Diabetes, or Type 2 diabetes with evidence of end-organ disease
- •Pregnant women who need to be emergently delivered due to maternal or fetal complications of pregnancy
研究组 & 干预措施
insulin pre-treatment
insulin pre-treatment of pregnant diabetic patients who receive betamethasone
干预措施: insulin pre-treatment (Drug)
结局指标
主要结局
Number of hospital days until euglycemia in pregnant diabetic patients receiving steroids who are pre-treated with insulin.
时间窗: number of hospital days
Pregnant diabetic patients admitted to the hospital who receive steroids for fetal lung maturity will have their blood glucose levels checked before and after receiving steroids. Blood glucose levels will be checked fasting and postprandial until the levels are consistently less than 160. This will vary for patients, but will be on average 2 to 14 days.
次要结局
未报告次要终点