Examination of the response to rewards in people with alcohol consumption disorder by measuring their eye movements
- Conditions
- alcohol use disorder
- Registration Number
- DRKS00021814
- Lead Sponsor
- Zentralinstitut für Seelische Gesundheit Mannheim
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Subjects with alcohol use disorder:
• Men and women between the ages of 18 and 65
• Fulfillment of at least 2 and maximum of 5 of the criteria for an alcohol use disorder (Alcohol Use Disorder) according to DSM-V, corresponding to a mild to moderate alcohol consumption disorder
• Adequate ability to communicate with the examiner to answer questions verbally and in writing
• Ability to consent after detailed written clarification (Fully Informed Consent)
• Normal or correctable (with contact lenses) poor eyesight
• abstinence from alcohol on Test day
Healthy subjects in the control group:
• Men and women between the ages of 18 and 65
• Alcohol consumption on a maximum of 5 days a week, a maximum of 12 g each alcohol per day for women (equivalent to 0.3 l beer; 0.125 l wine) and 24 g alcohol per day for men (corresponding to 0.6 l beer; 0.25 l wine)
• Adequate ability to communicate with the examiner to answer questions verbally and in writing
• Ability to consent after detailed written clarification (Fully Informed Consent)
• Normal or correctable (with contact lenses) poor eyesight
• abstinence from alcohol on test day
Subjects with alcohol use disorder:
• Withdrawal of the declaration of consent
• Alcohol consumption on the day of the examination (breath alcohol concentration> 0.3 ‰)
• Axis I disorder DSM 5 (except alcohol consumption disorder and Nicotine use disorder) within the past 12 months
• Pharmacotherapy with psychoactive substances within the past 14 days (except for stable doses of non-dopamine-active antidepressants and neuroleptics)
• Current drug abuse (THC, amphetamine, opiates, Benzodiazepines, barbiturates and cocaine)
• Not able to communicate with the examiner
• wearing glasses (without the possibility to wear contact lenses)
• Parkinson's disease
• History of withdrawal delirium or seizures
• Withdrawal symptoms determined via Clinical Institute Withdrawal Assessment for Alcohol Score (Score> 4)
Healthy subjects in the control group:
• Withdrawal of the declaration of consent
• Fulfillment of> = 1 Alcohol Use Disorder criteria according to DSM-V
• Alcohol consumption on the day of the examination (breath alcohol concentration> 0.3 ‰)
• Axis I disorder DSM 5 (except alcohol use disorder and Nicotine use disorder) within the past 12 months
• Pharmacotherapy with psychoactive substances within the past 14 days (except for stable doses of non-dopamine-active antidepressants and neuroleptics)
• Current drug abuse (THC, amphetamine, opiates, Benzodiazepines, barbiturates and cocaine)
• Not able to communicate with the examiner
• wearing glasses (without the possibility to wear contact lenses)
• Parkinson's disease
• History of withdrawal delirium or seizures
• Withdrawal symptoms determined via Clinical Institute Withdrawal Assessment for Alcohol Score (Score> 4)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method