KCT0009607
Not yet recruiting
未知
Postoperative conventional versus hypofractionated intensity-modulated radiation therapy with concurrent chemotherapy in cervical cancer: A prospective multicenter randomized phase III trial (POHIM_P3 trial)
ConditionsNeoplasms
Overview
- Phase
- 未知
- Status
- Not yet recruiting
- Sponsor
- Samsung Medical Center
- Enrollment
- 284
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional Study
Eligibility Criteria
- Ages
- 20(Year) to 75(Year) (—)
- Sex
- Female
Inclusion Criteria
- •(1\) Histologically confirmed cervical cancer
- •(2\) Histologically confirmed Squamous cell carcinoma, Adenocarcinoma or Adenosquamous carcinoma
- •(3\) Patients who underwent radical hysterectomy and pelvic lymph node dissection
- •(4\) Patients with pathological indications for radiotherapy
- •A. Pelvic lymph node metastasis
- •B.Parametrium involvement
- •C.Positive surgical margins
- •(5\) Age 20 \- 75 years
- •(6\) ECOG performance status 0\-1
- •(7\) Adequate bone marrow function: Granulocytes \=1\.0 x 103/µl, Platelets \=30 x 103/µl, Hemoglobin \=9\.5 g/dl
Exclusion Criteria
- •(1\) Distant metastasis
- •(2\) Previous pelvic radiotherapy
- •(3\) More than 3 Months post\-radical hysterectomy
- •(4\) Untreated serious acute disease without Cervical cancer
- •(5\) Nooadjuvant chemotherapy
- •(6\) Inability to undergo concurrent chemoradiotherapy
- •(7\) History of other cancer within 5 years (except for thyroid cancer, skin cancer, carcinoma in situ)
Investigators
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