To reduce the Pre operative anxiety before various surgical procedures under General Anaesthesia, buy using various drugs like Oral Melatonin, Oral Alprazolam, Combination of both and Placebo
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/02/031184
- Lead Sponsor
- andeeshwara D K
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 144
Inclusion Criteria
1.Age: 18years to 60 years
2.ASA 1 and 2
3.Surgery planned under General anaesthesia
Exclusion Criteria
1. Patient with current/past history of mental illness, neuropsychiatric disease, h/o substance abuse
2. History of known allergy to the study drugs
3. Patients who had taken drugs which may cause sedation in last 12hours,
4. History of intake of antiepileptics, antidepressants or antipsychotics, and immunosuppressive medications
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Combination of oral melatonin(3mg) +Alprazolam(0.25mg) is better than either drug alone as premedication in reducing anxiety in adult patients undergoing surgery under general anaesthesia.Timepoint: In the preoperative area before shifting to operation theatre
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI