Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes

Not yet recruiting

• Conditions: Type 1 Diabetes

• Registration Number: NCT05892848
• Lead Sponsor: Sohag University

Brief Summary

Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes have concluded that bone is negatively affected in type 1 diabetes with impaired bone density,increased fracture risk and impaired bone turnover markers.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-05
• Study First Submitted: 2023-05-29
• Study First Submitted QC: 2023-05-29
• Last Update Submitted: 2023-05-29
• Study First Posted: 2023-06-07
• Last Update Posted: 2023-06-07
• Study Start: 2023-06-10
• Primary Completion: 2024-06-30
• Study Completion: 2024-06-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• childern and adolsecents below 16 years of age diagnsed with type 1 diabetes for at least 1 year age and sex-matched control childern and adolsecents will be included

Exclusion Criteria

• childern and adolescents with congenital bone disease, those with disorders of the parathyroid gland and those with chronic kidney disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control	12 months	markers of bone turnover in patients with type 1 diabetes and their matched control

Trial Locations

Locations (1)

Sohag university Hospital; 🇪🇬 Sohag, Egypt