Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Not yet recruiting
- Conditions
- Type 1 Diabetes
- Interventions
- Diagnostic Test: serum ostecalcin,serum sclerostin and parathroid profile
- Registration Number
- NCT05892848
- Lead Sponsor
- Sohag University
- Brief Summary
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes have concluded that bone is negatively affected in type 1 diabetes with impaired bone density,increased fracture risk and impaired bone turnover markers.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- childern and adolsecents below 16 years of age diagnsed with type 1 diabetes for at least 1 year age and sex-matched control childern and adolsecents will be included
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Exclusion Criteria
- childern and adolescents with congenital bone disease, those with disorders of the parathyroid gland and those with chronic kidney disease.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description control group serum ostecalcin,serum sclerostin and parathroid profile age and sex matched control childern and adolsecents cases group serum ostecalcin,serum sclerostin and parathroid profile childern and adolescents with type 1 diabetes
- Primary Outcome Measures
Name Time Method level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control 12 months markers of bone turnover in patients with type 1 diabetes and their matched control
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Sohag university Hospital
🇪🇬Sohag, Egypt