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Clinical Trials/NCT05892848
NCT05892848
Not yet recruiting
Not Applicable

Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes

Sohag University1 site in 1 country100 target enrollmentJune 10, 2023
ConditionsType 1 Diabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 1 Diabetes
Sponsor
Sohag University
Enrollment
100
Locations
1
Primary Endpoint
level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes have concluded that bone is negatively affected in type 1 diabetes with impaired bone density,increased fracture risk and impaired bone turnover markers.

Registry
clinicaltrials.gov
Start Date
June 10, 2023
End Date
June 30, 2024
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hager Momen Ismail

Resident-pediatric department-sohag hospital university

Sohag University

Eligibility Criteria

Inclusion Criteria

  • childern and adolsecents below 16 years of age diagnsed with type 1 diabetes for at least 1 year age and sex-matched control childern and adolsecents will be included

Exclusion Criteria

  • childern and adolescents with congenital bone disease, those with disorders of the parathyroid gland and those with chronic kidney disease.

Outcomes

Primary Outcomes

level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control

Time Frame: 12 months

markers of bone turnover in patients with type 1 diabetes and their matched control

Study Sites (1)

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