Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Type 1 Diabetes
- Sponsor
- Sohag University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes have concluded that bone is negatively affected in type 1 diabetes with impaired bone density,increased fracture risk and impaired bone turnover markers.
Investigators
Hager Momen Ismail
Resident-pediatric department-sohag hospital university
Sohag University
Eligibility Criteria
Inclusion Criteria
- •childern and adolsecents below 16 years of age diagnsed with type 1 diabetes for at least 1 year age and sex-matched control childern and adolsecents will be included
Exclusion Criteria
- •childern and adolescents with congenital bone disease, those with disorders of the parathyroid gland and those with chronic kidney disease.
Outcomes
Primary Outcomes
level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control
Time Frame: 12 months
markers of bone turnover in patients with type 1 diabetes and their matched control