Evaluation of effects of methylprednisolone injection in masseter muscle versus deltoid muscle after wisdom tooth removal

Completed

• Conditions: Impacted teeth,

• Registration Number: CTRI/2022/06/043230
• Lead Sponsor: The Director

Brief Summary

The aim of the randomized controlled trial is to compare efficacy of methylprednisolone administration in masseter muscle versus deltoid muscle on postoperative sequalae in minor oral surgery. Patients with partially or completely bony/soft tissue impacted mandibular third molars with age group of 20-40 years will be included in the study. The primary and secondary parameters for comparison includes pain, facial edma, maximum interincisal opening, wound healing assessment and total number of postoperative analgesics taken by patient. Clinical assessment of the patients will be done on the day of surgery and first, third and seventh day postoperatively.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-15
• Study Completion: 2022-10-10
• Last Update Posted: 2023-04-20

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Partially or completely bony/soft tissue impacted mandibular third molars.
• Age group 20-40 years.

Exclusion Criteria

• Acute infection of odontogenic and non-odontogenic causes.
• Pregnant and lactating females.
• Patients with known systemic disorder such as diabetes mellitus, hypertension, thyroid disorder, immunocompromised state etc.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Comparison of mean pain intensity scores of group 1 and group 2 as assessed by visual analogue scale.	Preoperatively on the day zero (day of surgery) and on the first, third, and seventh post-operative days.
2. Comparison of facial edema as assessed by mean distance between : Tragus and lip commissure, tragus and soft tissue pogonion, gonion and external canthus of eye of group 1 and group 2.	Preoperatively on the day zero (day of surgery) and on the first, third, and seventh post-operative days.
3. Comparison of mean values of maximum interincisal opening of group 1 and group 2.	Preoperatively on the day zero (day of surgery) and on the first, third, and seventh post-operative days.

Secondary Outcome Measures

Name	Time	Method
1. Comparison of mean scores of wound healing of group 1 and group 2 as assessed by healing index by Landry et al.	2. Comparison of total number of postoperative analgesics taken for group 1 and group 2.

Trial Locations

Locations (1)

Lady Hardinge Medical College; 🇮🇳 Delhi, DELHI, India

Lady Hardinge Medical College

🇮🇳Delhi, DELHI, India

Dr Pravesh Mehra

Principal investigator

7982141142

csrmehra@gmail.com