NCT00192842已完成2 期
Phase II Trial of Gemcitabine and Curcumin in Patients With Advanced Pancreatic Cancer
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 17
- 主要终点
- time to tumor progression
研究概览
简要总结
The study hypotheasis is that curcumin, a natural compound with a potent antiproliferative effect, can improve the efficacy of the standard chemotherapy gemcitabine in patients with advanced pancreatic cancer. That is why the patients are given a daily oral dose of 8 gr of curcumin along the chemotherapeutic protocol of weekly gemcitabine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •locally advanced or metastatic adenocarcinoma of the pancreas
- •no prior chemotherapy
- •performance status 0-2
- •adequate hematology and chemistry
排除标准
- •serious concurrent medical condition
结局指标
主要结局
time to tumor progression
次要结局
- response rate
- survival
- clinical benefit
- toxicity
研究者
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