Evaluation of a MRI-based Clinico-radiomics Model in Predicting Lymph Node Metastasis Status of Hilar Cholangiocarcinoma Patients: a Prospective Diagnostic Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Lymph node metastasis status
研究概览
简要总结
This is a prospective, observational diagnostic study aiming to assess multiparametric MRI-based clinico-radiomics for identifying lymph node metastasis status in hilar cholangiocarcinoma.
详细描述
A preoperative tool capable of predicting lymph node metastasis status in hilar cholangiocarcinoma is lacking and urgently needed for clinical practice. This study proposes to establish and evaluate a machine-learning algorithms of multiparametric MRI-based clinico-radiomics for identifying lymph node metastasis status in hilar cholangiocarcinoma. This study will investigate the relationship between radiomic depth information and tumor biological characteristics. The study includes the construction of capable MRI-based clinico-radiomics prediction model and the validation of the prediction model.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patient must sign an informed consent form;
- •Age 18-75 years old, both male and female;
- •ECOG performance status score (PS score) 0-2;
- •Hilar cholangiocarcinoma with resectable tumor lesions;
- •Complete the upper abdomen MRI examination before treatment;
排除标准
- •Accompanied with other primary malignant tumors;
- •Patients who have neoadjuvant chemotherapy or other tumor-targeted therapies;
- •Incomplete imaging or medical history data.
结局指标
主要结局
Lymph node metastasis status
时间窗: Baseline
The value of multiparametric MRI-based clinico-radiomics in predicting lymph node metastasis.
次要结局
未报告次要终点