Study on 90% effective dose of ropivacaine for combined epidural anesthesia in patients with diabetic foot
Phase 1
- Conditions
- Diabetic foot
- Registration Number
- ChiCTR2400088926
- Lead Sponsor
- Hainan General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
In this study, patients diagnosed with diabetic foot debridement and drainage, toe amputation or foot amputation in Hainan Provincial People's Hospital were selected, and the patients agreed to the anesthesia method of lumbo-epidural anesthesia. All patients signed informed consent, regardless of gender or age, BMI<35kg/m2, and ASA grade I-III.
Exclusion Criteria
Patients with contraindications for intraspinal anesthesia such as spinal cord or radiculopathy, systemic severe infection or injection site infection, cotting dysfunction, allergy to amide local anesthetics, pre-existing sensory loss, inability to communicate with normal language, pregnant and lactating women, and participants in other clinical trials.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ED90 of ropivacaine based on successful or failed subarachnoid injection;
- Secondary Outcome Measures
Name Time Method Intraoperative Complications;Usage of vasoactive drugs;