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Robust antibody response after the third mRNA coronavirus vaccination in Japanese hemodialysis patients

Not Applicable
Completed
Conditions
COVID-19 in hemodialysis patients
Registration Number
JPRN-UMIN000049684
Lead Sponsor
Fujita Memorial Hospital, Internal Medicine
Brief Summary

After the third vaccination, 99.4% of the hemodialysis group and 100% of the control group were positive for antispike antibodies. Median antispike antibodies were 20,000 AU/mL (IQR, 7,729-37,000 AU/mL) in the hemodialysis group and 21,500 AU/ml (IQR, 14,000-32,250 AU/mL) in the healthcare worker group.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
294
Inclusion Criteria

Not provided

Exclusion Criteria

Patients with a history of COVID-19 prior to study entry or with a positive blood test for anti-SARS-CoV-2 IgG antibodies at the time of study entry

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Positive rate of SARS-CoV-2 IgG antibody 2-3 weeks after 3 doses of BNT162b2 mRNA vaccine
Secondary Outcome Measures
NameTimeMethod
Analysis of factors involved in the elevation of SARS-CoV-2 IgG antibodies in mRNA vaccines
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