Functional MRI of satiety, the interaction between gastric and oral stimulation and related hormones in healthy me

Completed

• Conditions: geen aandoening; Gaat om centrale regulatie van eetlust; No specific disease

• Registration Number: NL-OMON35878
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 15

Inclusion Criteria

Men, right-handed, normal weight (BMI between 20-25 kg/m2), age between 18 and 35 years, the willingness to be informed about possible brain abnormalities (incidental findings with MRI)

Exclusion Criteria

Not removable metal in body, smoking, excessive alcohol use, diet, medication use (different then paracetamol), claustrophobic.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Brain activation associated with the satiation process.<br /><br>2) Fasting serum concentrations of hormones involved in the satiation process.<br /><br>3) Measures of subjective ratings of hunger and fullness.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1) Subjective ratings of the desire to eat.<br /><br>2) Subjective ratings of anxiety.<br /><br>3) Energy intake (kJ) from the breakfast.</p><br>