Functional MRI of food reward 2
- Conditions
- geen aandoeningn.v.t.
- Registration Number
- NL-OMON38211
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
1. Healthy (self-reported) 2. Body Mass Index (BMI) between 20 and 25 kg/m2 3. Right-handed 4. Gender: female
1. Smoking 2. Having a food allergy 3. Having an eating disorder 4. Having a history of medical or surgical events that may significantly affect the study outcome, such as metabolic or endocrine disease, or any gastro-intestinal disorder 5. Use of medication, except aspirin/paracetamol and oral contraceptives 6. MRI exclusion criteria a) Claustrophobia b) Having metal implants (i.e. pacemaker, metal joints, prostheses, etc.) or metal objects on the body which cannot be removed (i.e. piercing, hearing aid, brace, etc. c) Being pregnant.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Neural activation (percentage signal change) induced by the presentation of<br /><br>pictures of food packages.</p><br>
- Secondary Outcome Measures
Name Time Method <p>- Reaction times during execution of the fMRI task.<br /><br>- Reported expected tastiness, purchase intention and perceived healthiness.<br /><br>- Eye movements during the execution of the MRI task.<br /><br>- Scores on 4 neuropsychological tasks: 1 ) a lexical decision-task (Kroese et<br /><br>al. 2010)<br /><br>2) a task which measures to what extent future rewards are discounted (temporal<br /><br>discounting task: Kirby, 1999)<br /><br>3) a task which measures the capacity to inhibit behaviour (STROOP)<br /><br>4) a task that measures working memory (N-Back)</p><br>