Functional MRI of food evaluation and choice

Completed

• Conditions: Geen aandoening; Gaat om voedsel evaluatie en keuze; No specific disease

• Registration Number: NL-OMON35918
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

1. Healthy (self-reported)
2. Age 20-40 at day 01 of the study
3. Body Mass Index (BMI) between 18 and 25 kg/m2
4. Right-handed
5. Having given their written informed consent
6. Willing to comply with the study procedures
7. Willing to accept use of all anonymized data, including publication, and the confidential use and storage of all data
8. Willing to be informed about chance findings of pathology and approving of the disclosure
of this information to the general physician (see Informed Consent

Exclusion Criteria

1.Smoking
2.Having a special diet (e.g. to lose weight, medically prescribed diet in the past 6 months, no meat etc)
3.Highly restraint eating (Van Strien et al., 1986).
4.Having a food allergy
5.Having gained or lost >5 kg of body weight in the past 6 months.
6.Having a history of or current alcohol consumption > 28 units per week
7.Having a history of medical or surgical events that may significantly affect the study outcome, such as metabolic or endocrine disease, or any gastro-intestinal disorder
8.Use of medication, except aspirin/paracetamol and contraceptives
9.Mental or physical status that is incompatible with the proper conduct of the study
10.Not having a general practitioner
11.Participation in any other clinical trial during this study.
12.Working at the Image Sciences Institute or the Radiology Department of the UMC Utrecht as employee or student.
13.MRI exclusion criteria
a)Claustrophobia
b)Having metal implants (i.e. pacemaker, metal joints, prostheses, etc.) or metal objects on the body which cannot be removed (i.e. piercing, hearing aid, brace, etc.
c)Being pregnant.
14. Taak gerelateerde exclusie criteria
a. Onsuccesvolle verzadiging (d.w.z. honger na de consumptie van test-maaltijd)
b. Misselijkheid

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Neural activation (percentage BOLD signal change) induced by the presentation<br /><br>of pictures of food and food choice. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Scores on liking task (LFPQ) & perceived caloric content<br /><br>2. Reaction times during execution of the fMRI choice task</p><br>