Functional MRI of food evaluation and choice in normal weight and overweight subjects across the lifespan.
Completed
- Conditions
- Overweight and obesity
- Registration Number
- NL-OMON26000
- Lead Sponsor
- niversity Medical Centre Utrecht
- Brief Summary
PMID: 29337278 DOI: 10.1016/j.neuroimage.2018.01.012, PMID: 34245869 DOI: 10.1016/j.neuroimage.2021.118374
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
1. Healthy (self-reported);
2. Age group 1: 8-10, group 2: 13 -17, group 3: 25-45 and group 4:65-75 at day 01 of the study;
Exclusion Criteria
1. Smoking;
2. Having a special diet (e.g. to lose weight, medically prescribed diet in the past 6 months, no meat etc);
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eural activation (percentage BOLD signal change) induced by the presentation of pictures of food and food choice.
- Secondary Outcome Measures
Name Time Method 1. Scores on LFPQ & perceived caloric content;<br /><br>2. Gut hormone levels during hungry and satiated condition on several time points;<br /><br>3. Neural activation (percentage signal change) in response the execution of a reward task.<br>