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Clinical Trials/CTRI/2017/08/009243
CTRI/2017/08/009243
Not yet recruiting
未知

To determine whether Pulse Pressure Variation correlates with Brachial artery velocity time integral and Carotid velocity time integral in predicting fluid responsiveness in patients undergoing major surgeries under general anesthesia with controlled mechanical ventilation. - nil

Tata Memorial Centre0 sites0 target enrollmentTBD
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ConditionsHealth Condition 1: null- Adult patients undergoing elective surgeries having major blood loss or fluid shifts requiring cardiac output monitoring under general anaesthesia

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: null- Adult patients undergoing elective surgeries having major blood loss or fluid shifts requiring cardiac output monitoring under general anaesthesia
Sponsor
Tata Memorial Centre
Status
Not yet recruiting
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Observational

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\.Adult patients (Age \> 18 yrs )
  • •2\.Elective surgeries cases having major blood loss or fluid shifts requiring cardiac output monitoring under general anaesthesia
  • •3\.Receiving lung ventilation 8 ml/kg PBW using Volume Assist Control mode.
  • •4\.With invasive arterial blood pressure monitoring and cardiac output monitoring using Flotrac EV1000

Exclusion Criteria

  • •1\.Age under 18 years
  • •2\.Patient in whom brachial artery could not be identified with certainty viz above elbow amputated patients and patient with known PVD.
  • •3\.absence of sinusrhythm,
  • •4\.presence of a ventricular assist device
  • •5\.Carotid artery stenosis( common carotid artery stenosis greater than 50 %(systolic peak velocity \>182 cm/s and/or diastolic velocity \>30 cm/s by Doppler ultrasound)\-as assessed by clinician from critical care with previous formal training in critical care ultrasound
  • •6\.contraindication to the prespecified ventilatory parameters (a period of passive ventilation at tidal volume \[Vt] 8 mL/kg of predicted body weight
  • •7\.Known heart failure and LVEF \< 40%
  • •8\.Valvular heart disease
  • •9\.Aortic insufficiency
  • •10\.Air leakage through chest drains

Outcomes

Primary Outcomes

Not specified

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