To determine whether Pulse Pressure Variation correlates with Brachial artery velocity time integral and Carotid velocity time integral in predicting fluid responsiveness in patients undergoing major surgeries under general anesthesia with controlled mechanical ventilation. - nil

Tata Memorial Centre0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1.Adult patients (Age > 18 yrs )
•2.Elective surgeries cases having major blood loss or fluid shifts requiring cardiac output monitoring under general anaesthesia
•3.Receiving lung ventilation 8 ml/kg PBW using Volume Assist Control mode.
•4.With invasive arterial blood pressure monitoring and cardiac output monitoring using Flotrac EV1000

•1.Age under 18 years
•2.Patient in whom brachial artery could not be identified with certainty viz above elbow amputated patients and patient with known PVD.
•3.absence of sinusrhythm,
•4.presence of a ventricular assist device
•5.Carotid artery stenosis( common carotid artery stenosis greater than 50 %(systolic peak velocity >182 cm/s and/or diastolic velocity >30 cm/s by Doppler ultrasound)-as assessed by clinician from critical care with previous formal training in critical care ultrasound
•6.contraindication to the prespecified ventilatory parameters (a period of passive ventilation at tidal volume [Vt] 8 mL/kg of predicted body weight
•7.Known heart failure and LVEF < 40%
•8.Valvular heart disease
•9.Aortic insufficiency
•10.Air leakage through chest drains
•11.spontaneous respiratory efforts

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