The effect of lidocaine administration during general anesthesia on inflammatory prognostic scores in breast cancer surgery candidates
Phase 2
- Conditions
- Breast cancer.Breast, unspecified
- Registration Number
- IRCT201608029593N5
- Lead Sponsor
- Vice chancellor for research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 63
Inclusion Criteria
Breast cancer patients candidate for elective mastectomy;ASA class I, II
Exclusion criteria: History of epilepsy; psychotic disorders; using anti-psychotic drugs; hepatic failure; elevated liver enzymes;renal failure; cardiac dysrhythmia; hospital admission more than 5 days; infection in last 14 days; drug allergic reaction to lidocaine; blood transfusion in last week; blood transfusion during or after surgery; surgery duration more than 4 hours; drug abuse are exclusion criteria
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eutrophil to lymphocyte ratio. Timepoint: 0, 6, 24, 48 hours and 14 days after surgery. Method of measurement: Calculation of the ratio by researcher.;Glasgow prognostic score. Timepoint: 0, 6, 24, 48 hours and 14 days after surgery. Method of measurement: Calculation of the score by researcher.
- Secondary Outcome Measures
Name Time Method C reactive protein. Timepoint: 0, 6, 24, 48 hours and 14 days after surgery. Method of measurement: Based on mg/dL using laboratory kit.;Albumin. Timepoint: 0, 6, 24, 48 hours and 14 days after surgery. Method of measurement: Based on mg/dL using laboratory kit.;Complete blood count (CBC). Timepoint: 0, 6, 24, 48 hours and 14 days after surgery. Method of measurement: Based on count/mm3 using laboratory kit.