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Clinical Trials/TCTR20240425003
TCTR20240425003
Completed
Phase 3

A Comparison Between Hemodialysis and Pre-dilution High Volume Online Hemodiafiltration for The Removal of Protein-bound Uremic Toxins Using Super High-flux Dialyzers: A Randomized Prospective Crossover Equality Study

Faculty of Medicine, Chulalongkorn University0 sites16 target enrollmentApril 25, 2024

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Protein bound uremic toxins removal in chronic hemodialysisSmall, middle and large molecular weight uremic toxins removal in chronic hemodialysis patients
Sponsor
Faculty of Medicine, Chulalongkorn University
Enrollment
16
Status
Completed
Last Updated
last year

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 25, 2024
End Date
April 20, 2024
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Hemodialysis patients with dialysis vintage at King Chulalongkorn Memorial hospital for more than 3 months
  • Adequate hemodialysis by Kt/V as the recommended guideline
  • Urine output less than 100 ml/day
  • Stable hemodynamic for at least 2 weeks before entering the research

Exclusion Criteria

  • Active cardiovascular disease, active severe infection
  • Severe dialyzer allergy
  • Malnutrition requiring intradialytic parenteral nutrition
  • Cirrhosis child C or decompensated cirrhosis
  • Advance stage malignancy
  • Have a chance to get living related kidney transplant within 1 year
  • Unwilling to participate the project

Outcomes

Primary Outcomes

Not specified

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