Investigating the effect of bevacizumab in reducing postoperative hemorrhage

Phase 4

• Conditions: Vitreous hemorrhage.; Vitreous hemorrhage; H43.1

• Registration Number: IRCT20231209060315N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Age more than 18 y/o
Patients with advanced proliferative diabetic retinopathy who have undergone vitrectomy surgery and silicone oil injection.
Six months or more have passed since the vitrectomy and the patient is a candidate for silicone oil drainage surgery
Totally attached retina.

Exclusion Criteria

Iris neovascularization
Neovascular glaucoma
Uncontrolled intraocular pressure
Optic atrophy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vitreous hemorrhage. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Examination.;Vitreous hemorrhage severity. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Examination.;Iris neovascularization. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Examination.;Neovascular glaucoma. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Slit-lamp examination and Goldman tonometery.;Retinal neovascularization. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Slit-lamp examination and indirect ophthalmoscopy.

Secondary Outcome Measures

Name	Time	Method
Retinal detachment. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Slit-lamp examination and indirect ophthalmoscopy.;Best Corrected Visual Acuity. Timepoint: Before intra-silicone injection, Days 1, 7, 30, and 90 after surgery. Method of measurement: Snellen chart.