Treatment of Mild and Subthreshold Depressive Disorders
Phase 4
- Conditions
- Depression
- Registration Number
- NCT00226642
- Lead Sponsor
- Ludwig-Maximilians - University of Munich
- Brief Summary
The purpose of this study is to determine the efficacy of a SSRI, cognitive-bahavioral-therapy and a free choice between SSRI and CBT in a sample of primary care patients suffering from mild to moderate depression.
Hypotheses:
* SSRI is superior to placebo
* CBT is superior to a non-specific supporting group therapy
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 369
Inclusion Criteria
(e.g.)
- subthreshold and mild depressive disorders including dysthymia (HAMD: 8-22)
- informed consent
- 18 years
Exclusion Criteria
(e.g.)
- severe mood disorders
- bipolar disorder
- recurrent brief depression
- suicidality
- alcohol or drug dependency
- obsessive-compulsive disorder
- schizoaffective disorder / schizophrenia
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method HAMD (changes between baseline and individual endpoint) IDS (changes between baseline and individual endpoint)
- Secondary Outcome Measures
Name Time Method CGI (changes between baseline and individual endpoint) BDI (changes between baseline and individual endpoint)
Trial Locations
- Locations (1)
Ludwig-Maximilians-University, Department of Psychiatry
🇩🇪Munich, Germany
Ludwig-Maximilians-University, Department of Psychiatry🇩🇪Munich, Germany