Magnesium and TKA Pain

Not Applicable

• Conditions: Pain
• Interventions: Drug: Magnesium Sulfate

• Registration Number: NCT01945437
• Lead Sponsor: Seoul National University Bundang Hospital

Brief Summary

The hypothesis of this study is that in staged bilateral total knee arthroplasty (TKA, magnesium sulfate administered during the perioperative period of the first TKA may decrease pain after the second TKA. It is known that pain is greater in the second TKA than in the first. Therefore, we compared pain of the second TKA between the magnesium and control groups.

Detailed Description

Not available

Study Timeline

• Status Verified: 2013-09
• Study First Submitted: 2013-09-13
• Study First Submitted QC: 2013-09-13
• Last Update Submitted: 2013-09-13
• Study First Posted: 2013-09-18
• Last Update Posted: 2013-09-18
• Study Start: 2014-01
• Primary Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

American society of anesthesiologist physical status 1 - 2. patients scheduled to undergo staged bilateral TKA

Exclusion Criteria

American society of anesthesiologist physical status >3

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
magnesium	Magnesium Sulfate	This group receive magnesium sulfate perioperatively.

Primary Outcome Measures

Name	Time	Method
Pain	from the end of the TKA until 48 hour	Pain measured with visual analogue scale (VAS)

Secondary Outcome Measures

Name	Time	Method
analgesic	from the end of the TKA until 48 hours	analgesic consumptions from the end of the TKA until 48 hours