Inhalation of Lidocaine Before Intubation
- Registration Number
- NCT01838993
- Lead Sponsor
- New Taipei City Hospital
- Brief Summary
We investigate the potential benefits of ultrasound-driven lidocaine inhalation immediately before induction.
- Detailed Description
Sudden increases in blood pressure and heart rate after tracheal intubation and post-operative sore throat are two common undesirable side effects of general anesthesia and might lead to patients' morbidity or dissatisfaction. We investigated the possibility to attenuate both side effects with one single method, i.e. ultrasound-driven lidocaine inhalation immediately before induction.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
- American Society of Anesthesiologists (ASA) physical status I or II. Patients scheduled for elective surgery under general anesthesia with orotracheal intubation
Exclusion Criteria
- patient's refusal to join, major surgery or expected operation duration longer than 3 hours, patients with a anticipated difficult airway, requiring a nasogastric tube in peri-operative stage, having recent upper respiratory tract infection (within 1 week) or pre-existing sore throat.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Control Placebo Normal saline inhalation before intubation Lidocaine Lidocaine inhalation Inhalation of lidocaine before intubation
- Primary Outcome Measures
Name Time Method Blood pressure 3 min Non invasive blood pressure every min for 3 min
- Secondary Outcome Measures
Name Time Method Post operative sore throat 3 days Questionnaire for Post operative sore throat
Trial Locations
- Locations (1)
New Taipei City Hospital
🇨🇳New Taipei City, Taiwan