NCT07120581进行中（未招募）不适用
Hyperbaric Oxygen Therapy as Salvage Therapy for Healthy, Severely Injured, Mechanically Ventilated Invasive Fungal Infection Cases Resistant to Therapy
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 7
- 试验地点
- 1
- 主要终点
- Eradication of Fungal Infectious Agent
研究概览
简要总结
The goal of this observational study is to learn about the effects of Hyperbaric Oxygen Therapy on healthy individual who suffer from invasive fungal infection caused by severe trauma, who do not respond to conventional treatment. The main question it aims to answer is:
Does the treatment aid in eradicating the infection and improve the overall outcome of such patients?
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •at least 18 year old
- •Trauma as the insult type causing the infection
- •Refractory IFI with failure to respond to standard therapy (medical and surgical)
- •Hyperbaric Oxygen Therapy as part of the treatment
排除标准
- •Patients who did not recieve hyperbaric oxygen therapy as part of the treatment
- •Patients with immunosuppression background
结局指标
主要结局
Eradication of Fungal Infectious Agent
时间窗: From enrollment, baseline day 1, through study completion, an average of 4-8 weeks
The time it takes from the start of treatments and until the first negative culture was found.
次要结局
- Clinical Status on Discharge- ventilation status(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
- clinical status on discharge- kidney function(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
- clinical status on discharge- Kidney function(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
- clinical status on discharge- consciousness level(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
- clinical status on discharge- wound status(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
- clinical status on discharge- location of discharge(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
- Adverse Events(From enrollment, baseline day 1, through study completion, an average of 4-8 weeks)
研究者
Reudor Grinberg
Intensive Care Physician
Assaf-Harofeh Medical Center
研究点 (1)
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