NCT07489417RecruitingNot Applicable
Impact of Sleep Restriction on Blood Pressure Reactivity
University of Missouri-Columbia1 site in 1 country45 target enrollmentStarted: March 4, 2026Last updated:
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Mean Blood Pressure
Study Overview
Brief Summary
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 45 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy adult men and women
- •18-45 years of age
- •BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
- •Non-pregnant, non-breastfeeding, and non-nicotine users
- •Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
- •Premenopausal
Exclusion Criteria
- •No acute or chronic conditions
- •Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
- •Self-reported history of irregular sleep
- •Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension
Arms & Interventions
Sleep Restriction
Experimental
You will be asked to shorten your sleep to four hours.
Intervention: Sleep Restriction (Behavioral)
Normal Sleep
No Intervention
You will be asked to sleep for 7-9 hours.
Outcomes
Primary Outcomes
Mean Blood Pressure
Time Frame: Baseline and during the last 1-minute of stress
Mean Blood pressure
Blood Pressure
Time Frame: Baseline and during the last 1-minute of stress
Blood pressure
Secondary Outcomes
No secondary outcomes reported
Investigators
Jacqueline K Limberg, PhD
Associate Professor
University of Missouri-Columbia
Study Sites (1)
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