Postoperative hormonal changes in thyroid hormones after placement of a plastic tracheostoma
Phase 4
- Conditions
- Malignant neoplasm of the oral cavityC02C03C04C05C06C07C08C00Malignant neoplasm of other and unspecified parts of tongue
- Registration Number
- DRKS00023942
- Lead Sponsor
- niversitätsklinikum Schleswig-Holstein Campus Kiel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 51
Inclusion Criteria
Patients of the Oral and Maxillofacial Surgery at Kiel University Hospital
Exclusion Criteria
Not able to consent
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method We hope to be able to select the most thyroid-sparing method for tracheostomy and to optimize patient care for future patients. <br>Laboratory parameters of the thyroid gland (TSH, T3, T4) are determined immediately before surgery, one day after surgery, immediately before closure of the tracheostoma, and one day after closure of the tracheostoma.<br>Laboratory parameters are collected by blood sampling.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does plastic tracheostoma placement affect thyroid hormone synthesis in patients with C00-C08 oral cavity malignancies?
What molecular pathways link tracheostomy-induced inflammation to postoperative thyroid hormone dysregulation in head and neck cancer patients?
Are there predictive biomarkers for thyroid hormone recovery after tracheostoma in malignant neoplasm of the parotid gland (C08)?
What adverse events are associated with prolonged thyroid hormone suppression post-tracheostomy in oral cancer patients?
How does DRKS00023942 compare plastic tracheostoma outcomes to standard-of-care tracheostomy in thyroid hormone preservation for C02-C08 cancers?