Effect of high dose oral Acetyl-L-carnitine on ischemic stroke
Phase 2
Recruiting
- Conditions
- ischemic stroke.Cerebral infarction
- Registration Number
- IRCT20150629022965N14
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
age 18 to 85 years
focal neurological disorder
Clinical diagnosis of hemispheric acute ischemic stroke
Radiological findings in MRI and CT scan consistent with clinical diagnosis of acute hemispheric stroke
No other inflammatory disease at same time
Not using other drugs that alter the level of outcomes of this study
no Pregnancy and lactation
Patients who have been admitted for the first 24 hours after the stroke.
Patients who have had an ischemic stroke for the first time.
Exclusion Criteria
Existing evidence show acute or chronic intracerebral hemorrhage and brain aneurysm
The presence of any other etiology except ischemia
The presence of any cognitive or behavioral impairment that leads to a patient's lack of cooperation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of IL-6. Timepoint: before intervention and 3 days after intervention. Method of measurement: ELISA kit.;Serum level of TNF-alpha. Timepoint: before intervention and 3 days after intervention. Method of measurement: ELISA kit.;Serum level of NSE. Timepoint: before intervention and 3 days after intervention. Method of measurement: ELISA kit.;Serum level of ICAM-1. Timepoint: before intervention and 3 days after intervention. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: 3 days after intervention. Method of measurement: Clinical examination.