NCT02885064已完成不适用
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Change from Baseline to Month 6 in Clusters Of Orthologous Groups of proteins
研究概览
简要总结
This study is observational only and is intended to evaluate changes in the makeup and function of bacteria naturally present in the mouth during treatment with braces to straighten teeth.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 8 Years 至 99 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA I or II (ASA I is a healthy patient, ASA II is patient with minor systemic disease)
- •Patient must be receiving orthodontic treatment at the University of North Carolina School of Dentistry and not yet be in active treatment
排除标准
- •Patients who have used antibacterial therapy in the past 3 months
- •Patients who report current smoking
- •ASA III or above (Patients with severe systemic diseases)
结局指标
主要结局
Change from Baseline to Month 6 in Clusters Of Orthologous Groups of proteins
时间窗: Baseline, Month 6
Change in Shannon diversity index from Baseline to Month 6
时间窗: Baseline, Month 6
次要结局
- Change in gingival index(Baseline, Month 6)
- Change in decalcification index(Baseline, Month 6)
研究者
研究点 (1)
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